TL;DR:
- Wintermute warned that the current macroeconomic framework puts Ethereum (ETH) at a disadvantage compared to other assets in the crypto industry.
- Ethereum fell 10.2% over the past week and faces institutional selling of $88 million per day, according to Glassnode data.
- ETH open interest dropped $1 billion to $12.4 billion; more than 72% of long positions are at risk of liquidation.
Wintermute, one of the most important market making firms in the crypto ecosystem, published an analysis warning that the current macroeconomic environment places Ethereum in a position of structural disadvantage relative to other assets. According to the firm, the combination of growing inflationary pressure and geopolitical uncertainty is making it harder for ETH to adapt to the ongoing market cycle.
Wintermute’s report notes that consumer price index (CPI) inflation in the United States reached 3.8% in April, after having been projected at 3.7% for March. Added to this is the tension in the Strait of Hormuz, which pushed Brent crude prices up 8.6% over the week, leaving the barrel trading above $102 once again. Federal Reserve futures no longer price in rate cuts and are even factoring in a hike in December, a historically unfavorable scenario for digital assets.
— Wintermute (@wintermute_t) May 19, 2026
Wintermute: Why Ethereum Is Vulnerable to Uncertainty
ETH fell 10.2% in nominal terms over the past week and lost ground against Bitcoin, trading at a ratio of 0.0275 BTC. The price found support around $2,100, a technical level analysts identify as a potential bounce zone. In that context, Bitcoin held within a range of $77,000 to $82,000, showing greater resilience.
Wintermute highlighted that institutional selling of ETH averaged $88 million per day, representing the strongest outflow period since February according to Glassnode data. Flows into Ethereum ETFs also weakened, signaling a deterioration in sentiment among both native ecosystem investors and institutional profiles.
Fear Takes Hold in the ETH Market
The market sentiment index for ETH dropped from 47 to 27 points in a week, entering fear territory. On Binance, the buyer-to-seller ratio in futures fell to 0.91%, a level historically associated with market corrections. The dominance of sellers deepened the bearish pressure on ETH.
Despite the short-term deterioration, certain structural indicators remain solid. Around 24.6 million ETH are held in accumulation addresses, and more than 31% of the total supply is locked in staking. Ethereum remains the primary hub of decentralized finance, which has so far held up without triggering liquidation cascades.
